| Autor: |
Taguchi, Akihiko, Blood, David C., Del Toro, Gustavo, Canet, Anthony, Lee, Daniel C., Qu, Wu, Tanji, Nozomu, Lu, Yan, Lalla, Evanthia, Fu, Caifeng, Hofmann, Marion A., Kislinger, Thomas, Ingram, Mark, Lu, Amy, Tanaka, Hidekazu, Hori, Osamu, Ogawa, Satoshi, Stern, David M., Schmidt, Ann Marie |
| Předmět: |
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| Zdroj: |
Nature; 5/18/2000, Vol. 405 Issue 6784, p354, 7p, 6 Color Photographs, 18 Black and White Photographs, 8 Graphs |
| Abstrakt: |
Reports on a study of the receptor for advanced glycation end products (RAGE), which is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. Interaction with molecules implicated in diabetes and Alzheimer's disease; Findings which demonstrate that blockade of RAGE-amphoterin decreased growth and metastases of both implanted tumors and tumors developing spontaneously in susceptible mice. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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