A Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis-Liquid Chromatography Tandem Mass Spectrometry Analysis of Bovine Cartilage Tissue Response to Mechanical Compression Injury and the Inflammatory Cytokines Tumor Necrosis Factor α and Interleukin-1β.

Autor: Stevens, Anna L., Wishnok, John S., Chai, Diana H., Grodzinsky, Alan J., Tannenbaum, Steven R.
Předmět:
Zdroj: Arthritis & Rheumatism; Feb2008, Vol. 58 Issue 2, p489-500, 12p, 1 Diagram, 2 Charts, 3 Graphs
Abstrakt: The article discusses an analysis of the response of bovine cartilage tissue and chondrocytes to injurious mechanical compressions and treatment with interleukin-1ß (IL-1&ß) and tumor necrosis factor α (TNFα). A combination of liquid chromatography and mass spectrometry was used in order to determine the response. It was found that cell membrane was disrupted because of the injurious compressions.
Databáze: Complementary Index