| Autor: |
Gein, V. L., Kasimova, N. N., Moiseev, A. L., Sheptukha, M. A., Syropyatov, B. Ya., Ismailova, N. G., Voronina, E. V., Ivanenko, O. I. |
| Předmět: |
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| Zdroj: |
Pharmaceutical Chemistry Journal; Sep2007, Vol. 41 Issue 9, p476-479, 4p, 1 Diagram, 3 Charts |
| Abstrakt: |
A series of 4-acyl-5-aryl-3-hydroxy-1-(2-hydroxyethylaminoethyl)-3-pyrrolin-2-ones (I) and their hydrochlorides (II) were synthesized via reactions of methyl esters of acylpyruvic acids with a mixture of aromatic aldehyde and N-hydroxyethylethylenediamine. The antibacterial activity of compounds I and the influence of compounds I and II on blood coagulation were studied. All compounds demonstrate pronounced anticoagulant or hemostatic action. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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