High birth weight as an important risk factor for infant leukemia.

Autor: Koifman, S., Pombo-de-Oliveira, M. S., Brazilian Collaborative Study Group of Infant Acute Leukemia
Předmět:
Zdroj: British Journal of Cancer; 2/5/2008, Vol. 98 Issue 3, p664-667, 4p, 2 Charts, 1 Graph
Abstrakt: In this paper, we compared the birth weight distribution among 201 infant leukaemia (IL) cases with that of 440 noncancer controls enrolled in Brazil in 1999-2005. Compared with the general population and the stratum 2500-2999 g as reference, IL cases weighing 3000-3999 g presented an odds ratio (OR) of 1.68 (95% CI: 1.03-2.76), and those of 4000 g or more, an OR of 2.28 (95% CI: 1.08-4.75), P trend<0.01. Using hospital-based controls, the OR for 4000 g or more, compared to 2500-2999 g, was 1.30 (95% CI: 1.02-1.43) after adjusting for confounders (gender, income, maternal age, pesticide and hormonal exposure during pregnancy). The results suggest that high birth weight is associated with increased risk of IL. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index