Autor: |
Pedro Paulo Vissotto de Paiva Diniz, Denise Saretta Schwartz, Helio Silva Autran de Morais, Edward Bealmear Breitschwerdt |
Předmět: |
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Zdroj: |
Vector-Borne & Zoonotic Diseases; Dec2007, Vol. 7 Issue 4, p689-698, 10p |
Abstrakt: |
For many vector-borne organisms, dogs can be used as sentinels to estimate the risk of human infection. The objective of this study was to use dogs as sentinels for multiple vector-borne organisms in order to evaluate the potential for human infection with these agents in southeastern Brazil. Blood from 198 sick dogs with clinicopathological abnormalities consistent with tick-borne infections were selected at the São Paulo State University Veterinary Teaching Hospital in Botucatu and tested for DNA andor antibodies against specific vector-borne pathogens. At least one organism was detected in 88 of the dogs, and Ehrlichia canisDNA was amplified from 78 of the blood samples. Bartonellaspp. seroreactivity was found in 3.6. Leishmania chagasiantibodies were detected in 1 of the dogs. There was no serological or polymerase chain reaction evidence of infection with Anaplasma phagocytophilum, Borrelia burgdorferi, Ehrlichia chaffeensis, Ehrlichia ewingii, and Rickettsia rickettsii. The full E. canis16S rRNA gene sequence of one of the Brazilian strains obtained in this study was identical to the causative agent of human ehrlichiosis in Venezuela. Ehrlichia canismay pose a human health hazard and may be undiagnosed in southeastern Brazil, whereas exposure to the other organisms examined in this study is presumably infrequent. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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