Therapeutic effects of antibodies to interleukin-5.
| Autor: | Cuss, F. M. |
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| Předmět: | |
| Zdroj: | Allergy; Sep1998 Supplement 45, Vol. 53, p89-92, 4p |
| Abstrakt: | The article discusses the role of interleukin-5 (IL-5) in asthma and other inflammatory diseases. It highlights the biosynthesis of IL-5 and the mechanism which is based on its production, release and receptor activation. The role of IL-5 in the generation and development of eosinophils in the bone-marrow compartment is discussed. It claims that the major source of IL-5 is the T cells while immunohistochemical studies reveals the synthesis of IL-5 by numerous cells such as eosinophils. |
| Databáze: | Complementary Index |
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