Screening of Southeastern Brazilian Mikania Species on Trypanosoma cruzi.

Autor:	Chaves, Juliana Siqueira, Nascimento, Andréa Mendes do, Soares, Adriana Pereira, Campos, Luciana Mattoso Pires de, Oliveira, Patrícia Abrão de, Albuquerque, Sérgio de, Oliveira, Dionéia Camilo Rodrigues de
Předmět:	MIKANIA TRYPANOSOMA cruzi DICHLOROMETHANE METHANOL PARASITES
Zdroj:	Pharmaceutical Biology; Dec2007, Vol. 45 Issue 10, p749-752, 4p, 2 Charts
Abstrakt:	Southeastern Brazilian Mikania (Asteraceae) species were evaluated for trypanocidal activity against the trypomastigote forms of Trypanosoma cruziat a concentration of 4000 µg/mL. Fourteen extracts were examined for in vitro trypanocidal properties. Of total extracts, 92.9% (13 extracts) exhibited trypanocidal effects. The dichloromethane extract of Mikania camporum B. Robinson and the methanol extract of Mikania micrantha H. B. K. caused 100% lysis of the parasites. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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