Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.

Autor: Alizadeh, Ash A., Eisen, Michael B., Davis, R. Eric, Ma, Chi, Lossos, Izidore S., Rosenwald, Andreas, Boldrick, Jennifer C., Sabet, Hajeer, Tran, Truc, Yu, Xin, Powell, John I., Yang, Liming, Marti, Gerald E., Moore, Troy, Hudson Jr., James, Lu, Lisheng, Lewis, David B., Tibshirani, Robert, Sherlock, Gavin, Chan, Wing C.
Předmět:
Zdroj: Nature; 2/3/2000, Vol. 403 Issue 6769, p503, 9p, 4 Diagrams, 3 Graphs
Abstrakt: Examines the molecular heterogeneity in the tumors of diffuse large B-cell lymphoma (DLBCL) patients. How researchers conducted a systematic characterization of gene expression in B-cell malignancies; Identification of two molecularly distinct forms of DLBCL; Observation that patients with germinal center B-like DLBCL had better survival rates than patients with activated B-like DLBCL; Conclusions.
Databáze: Complementary Index