| Autor: |
Swapna, I., Senthilkumaran, B. |
| Předmět: |
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| Zdroj: |
Fish Physiology & Biochemistry; Dec2007, Vol. 33 Issue 4, p335-345, 11p, 1 Diagram, 2 Charts |
| Abstrakt: |
Reproduction in fishes is influenced by thyroid hormones at various levels of gonadal cell differentiation and steroidogenesis. Thyroid hormones have recently also emerged as an important modulator of season- and photoperiod-dependent variations in the reproductive cycle with a possible effect on the hypothalamo–hypophyseal axis and pineal interactions. This review describes the current status of thyroid hormone research in relation to reproduction, with special emphasis on contributions to this field by Indian researchers including our laboratory. Evidence is provided for the multifocal action of thyroid hormones at various levels of the hypothalamo–hypophyseal–gonadal axis affecting reproduction. The underlying physiological and molecular mechanisms pertaining to thyroid hormone modulation of reproduction, such as gonadotropin-releasing hormone (GnRH) synthesis and release, androgen and gonadotropin receptor expression, gonadotropin (GTH) expression, and tissue sensitivity to GTHs are highlighted with relevant discussions of the current technical limitations, applications, and future perspectives of research in this field. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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