PLMaddon: a power-law module for the MatlabTM SBToolbox.

Autor: Julio Vera, Cheng Sun, Yvonne Oertel, Olaf Wolkenhauer
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Zdroj: Bioinformatics; Oct2007, Vol. 23 Issue 19, p2638-2638, 1p
Abstrakt: Summary: PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab ™ toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-laws logarithmic gains and sensitivities. Availability: PLMaddon is an open source module for the analysis of power-law models based on the SBToolbox. The latest version of PLMaddon is freely available from: www.sbi.uni-rostock.de/plmaddon The website contains a tutorial with examples, as well as an interactive introductory course on power-law models in systems biology. Contact: olaf.wolkenhauer@uni-rostock.de [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index