| Autor: |
Woodworth, J. C., Tokach, M. D., Nelssen, J. L., Goodband, R. D., Dritz, S. S., Koo, S. I., Minton, J. E., Owen, K. Q. |
| Předmět: |
|
| Zdroj: |
Journal of Animal Science; Oct2007, Vol. 85 Issue 10, p2524-2537, 14p, 4 Charts, 5 Graphs |
| Abstrakt: |
Gestating sows (n = 44; parity = 2.0; BW = 208 kg) were used to determine the effects of dietary ʟ-carnitine and Cr picolinate (CrP) on daily blood hormone and metabolite profiles. Diets were formulated as a 2 × 2 factorial with L-carnitine (0 or 50 ppm) and CrP (0 or 200 ppb) and were fed from breeding through gestation, lactation, and 28 d into the subsequent gestation, at which time blood collection occurred. Sows were fed 1 meal per day during gestation (2.04 kg from breeding until d 100 and 2.95 kg from d 100 until farrowing) and ad libitum during lactation. Sows were fitted with indwelling venous catheters, and blood (plasma) was collected at feeding, then once every 15 min for the first 3 h after feeding, and at 6, 9, 15, 20, and 24 h after feeding. Postfeeding and overall insulin and connecting peptide of insulin (c-peptide) was decreased for sows fed diets with CrP or ʟ-carnitine and was greatest for sows fed the control diet; however, sows fed both ʟ-carnitine and CrP had an intermediate response (ʟ-carnitine × CrP, P < 0.01). Postfeeding glucose peak was decreased (P < 0.05) in sows fed diets with ʟ-carnitine, CrP, or both, vs. the control, and mean glucose concentration was decreased (P < 0.01) for sows fed diets with CrP. ʟ-Carnitine decreased (P < 0.04) the NEFA concentration. Sows fed diets with CrP exhibited increased (P < 0.03) postfeeding and overall NEFA and greater (P < 0.02) fasting and overall glycerol. Overall plasma urea N was lowest for sows fed the diet with ʟ-carnitine; however, diets containing CrP had intermediate responses compared with the control (ʟ-carnitine × CrP, P < 0.005). Sows fed diets with ʟ-carnitine had greater (P < 0.008) IGF-I from 3 to 24 h after feeding and tended to exhibit greater (P < 0.06) overall IGFBP-3. Sows fed the diets with CrP had greater (P < 0.05) IGFBP-3 from 2 to 20 h after feeding. No differences were observed for glucagon or triacylglycerol (P > 0.10). The changes in metabolites and metabolic hormones indicate that both a-carnitine and CrP influence energy metabolism of gestating sows; however, their effects on blood hormones and metabolites differ. Thus, the improvement in energy status from adding both ʟ-carnitine and CrP may have an additive effect on reproductive performance of sows. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
