Acyl migration during alkylation of acetoxyurea derivatives.

Autor: Onuchina, O. A., Zaitsev, S. A., Levina, V. I., Grigor'ev, N. B., Chernyshev, V. V., Granik, V. G.
Předmět:
Zdroj: Pharmaceutical Chemistry Journal; Mar2007, Vol. 41 Issue 3, p160-165, 6p, 2 Diagrams, 6 Charts
Abstrakt: The alkylation of N-acetoxy-N-(benzofuran-2-yl)urea is performed in the presence of sodium hydride. This process is accompanied by the migration of the acetyl group with the formation of O-acetylisourea. The kinetic parameters of O-acetylisourea hydrolysis in basic and acidic media are determined. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index