| Autor: |
Shirshev, S. V., Kuklina, E. M., A. Yu.Maksimov, Krapivina, O. A., Parshakova, N. S. |
| Předmět: |
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| Zdroj: |
Biochemistry (00062979); Sep2007, Vol. 72 Issue 9, p983-988, 6p, 3 Diagrams |
| Abstrakt: |
The existence of αβT-lymphocyte differentiation processes have been demonstrated in mouse peripheral lymphoid organs during pregnancy. Study of pregnant Swiss mice has shown that the development of the second half of gestation is accompanied by expression of RAG-1 recombinase mRNA and unrearranged TCR α-chain (pre-TCRα) preferentially in T-lymphocytes of lymph nodes involved in uterine drainage (para-aortal lymph nodes), and to a lesser extent in other lymph nodes (mainly from axillary lymph nodes). The data suggest that during pregnancy the differentiation of αβT lymphocytes may occur not only in central (thymus) but also in peripheral lymphoid organs. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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