Transient hypoparathyroidism following thyroidectomy: A prospective study and multivariate analysis of 604 consecutive patients

Autor: Cavicchi, Ottavio, Piccin, Ottavio, Caliceti, Umberto, De Cataldis, Angelo, Pasquali, Renato, Ceroni, Alberto Rinaldi
Zdroj: Otolaryngology-Head & Neck Surgery; Oct2007, Vol. 137 Issue 4, p654-658, 5p
Abstrakt: Objective: The purpose of this study was to identify the risk factors for postoperative transient hypoparathyroidism in a group of patients undergoing thyroid surgery. Study Design: A prospective study was conducted on 604 patients undergoing thyroid surgery. Subjects and Methods: Gender, final diagnosis, extent of resection, biology of pathology, intrathoracic involvement, surgery for recurrent multinodular goiter, and presence and number of parathyroid glands in a surgical specimen were analyzed as risk factors for postoperative transient hypoparathyroidism. The chi-square test and a logistic regression analysis were applied. Results: On logistic regression analysis, only the extent of surgery constituted an independent variable for transient hypoparathyroidism (P = 0.001). Conclusion: The extent of surgery to central and/or lateral neck lymph nodes is responsible for a high rate of transient hypoparathyroidism owing to a high probability of unplanned parathyroidectomy or parathyroid gland devascularization. [Copyright &y& Elsevier]
Databáze: Complementary Index