Con-Struct Map: a comparative contact map analysis tool.

Autor: Jo-Lan Chung, John E. Beaver, Eric D. Scheeff, Philip E. Bourne
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Zdroj: Bioinformatics; Sep2007, Vol. 23 Issue 18, p2491-2491, 1p
Abstrakt: Summary: Con-Struct Map is a graphical tool for the comparative study of protein structures. The tool detects potential conserved residue contacts shared by multiple protein structures by superimposing their contact maps according to a multiple structure alignment. In general, Con-Struct Map allows the study of structural changes resulting from, e.g. sequence substitutions, or alternatively, the study of conserved components of a structure framework across structurally aligned proteins. Specific applications include the study of sequence-structure relationship in distantly related proteins and the comparisons of wild type and mutant proteins. Availability: http://pdbrs3.sdsc.edu/ConStructMap/viewer_argument_generator/singleArguments Contact: bourne@sdsc.edu Supplementary information: Supplementary data are available at Bioinformatics online. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index