Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients.

Autor: Boris Povazˇay, Boris Hermann, Angelika Unterhuber, Bernd Hofer, Harald Sattmann, Florian Zeiler, James E. Morgan, Christiane Falkner-Radler, Carl Glittenberg, Susanne Blinder, Wolfgang Drexler
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Zdroj: Journal of Biomedical Optics; Jul2007, Vol. 12 Issue 4, p41211-41211, 1p
Abstrakt: Frequency domain optical coherence tomography (FD-OCT), based on an all-reflective high-speed InGaAs spectrometer, operating in the 1050 nm wavelength region for retinal diagnostics, enables high-speed, volumetric imaging of retinal pathologies with greater penetration into choroidal tissue is compared to conventional 800 nm three-dimensional (3-D) ophthalmic FD-OCT systems. Furthermore, the lower scattering at this wavelength significantly improves imaging performance in cataract patients, thereby widening the clinical applicability of ophthalmic OCT. The clinical performance of two spectrometer-based ophthalmic 3-D OCT systems compared in respect to their clinical performance, one operating at 800 nm with 150 nm bandwidth (∼3 μm effective axial resolution) and the other at 1050 nm with 70 nm bandwidth (∼7 μm effective axial resolution). Results achieved with 3-D OCT at 1050 nm reveal, for the first time, decisive improvements in image quality for patients with retinal pathologies and clinically significant cataract. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index