Synthesis and Spectroscopic Structural Elucidation of New Quinoxaline Derivatives.

Autor:	Ghomsi, NathanTene, Ahabchane, Nour‐EddineHammou, Es‐Safi, Nour‐Eddine, Garrigues, Bernard, Essassi, ElMokhtar
Předmět:	QUINOXALINES SPECTRUM analysis ALKYLATION PHASE-transfer catalysis ORGANIC compounds
Zdroj:	Spectroscopy Letters; Sep2007, Vol. 40 Issue 5, p741-751, 11p, 4 Diagrams, 1 Chart, 2 Graphs
Abstrakt:	A quinoxaline-2,3-dione derivative was synthesized, and its chemical structure was determined through spectral analysis. Alkylation of this compound under phase transfer catalysis (PTC) conditions yielded monoalkylated and diakylated adducts. The monolalkylation process was shown to be regioselective occurring on the quinoxalic nitrogen atom rather than on its pyrazolic analogue. The full characterization of the synthesized compounds was studied by concerted use of NMR and MS techniques. Assignments of proton and carbon atoms were achieved through analysis of the 1D 1H and 13C NMR spectra combined with homo- and hetero-nuclear 2D NMR experiments. Determination of the alkylation site was achieved through long-range proton-carbon coupling correlations spectroscopy. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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