| Autor: |
Bedard, Anne‐Claude, Jain, Umesh, Johnson, Sheilah Hogg, Tannock, Rosemary |
| Předmět: |
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| Zdroj: |
Journal of Child Psychology; Sep2007, Vol. 48 Issue 9, p872-880, 9p, 2 Charts |
| Abstrakt: |
Background: To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in attention-deficit hyperactivity disorder (ADHD) and determine the responsiveness of WM measures to MPH. Methods: Participants were a clinical sample of 50 children and adolescents with ADHD, aged 6 to 16 years old, who participated in an acute randomized, double-blind, placebo-controlled, crossover trial with single challenges of three MPH doses. Four components of WM were investigated, which varied in processing demands (storage versus manipulation of information) and modality (auditory-verbal; visual-spatial), each of which was indexed by a minimum of two separate measures. Results: MPH improved the ability to store visual-spatial information irrespective of instrument used, but had no effects on the storage of auditory-verbal information. By contrast, MPH enhanced the ability to manipulate both auditory-verbal and visual-spatial information, although effects were instrument specific in both cases. Conclusions: MPH effects on WM are selective: they vary as a function of WM component and measurement. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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