Biomedical Applications of Cyclodextrin Based Polyrotaxanes.

Autor:	Loethen, Scott, Kim, Jong‐Mok, Thompson, DavidH.
Předmět:	CYCLODEXTRINS MEDICINE HYDROGELS DRUG delivery systems ANTINEOPLASTIC agents
Zdroj:	Polymer Reviews; 2007, Vol. 47 Issue 3, p383-418, 36p, 18 Diagrams, 3 Charts
Abstrakt:	Due to their controllable size, low cytotoxicity, and unique architecture, cyclodextrin-based polyrotaxanes and pseudopolyrotaxanes have been developed to encompass a broad range of diverse medical applications from erodable hydrogels to drug and gene delivery. This review summarizes the synthesis, characterization, dynamics, applications, and potential utility of cyclodextrin based polyrotaxanes and pseudopolyrotaxanes for medical applications. Specifically, this article reviews the literature appearing on this topic between 1999 and November 2006. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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