| Abstrakt: |
It has been postulated that increased blood pressure is related tohypersensitivity of arterial chemoreceptors and increased tissue oxygensupply. Arterial blood pressure has been found to be negatively correlatedto serum zinc and positively correlated to age, body mass index, andhemoglobin concentrations. The aim of the present investigation was tofurther explore the relationship between blood pressure and zinc concentrationsin serum and blood morphology parameters, iron concentrations,and venous blood gasometry parameters. The study was carried out in twogroups. Group Aconsisted of 23 subjects of both sexes suffering from moderateto severe arterial blood pressure. Their mean age was 53.13±10.45 yr(range: 23-74 yr). Group B included 48 subjects of mean age 36.7±10.0 yr(range: 26-60 yr). This group included 5 patients with arterial hypotension,37 with hypertension, and the remaining 6 with normal blood pressure.Significant positive correlations between serum zinc and red blood cellcount (r = 0.51) and negative with age (r = -0.52) were found. By multipleregression, negative correlations were also found between serum zinc andthe diastolic blood pressure and with hemoglobin (r = -0.5). Age was positivelycorrelated to systolic (r = 0.49) and diastolic (r = 0.45) blood pressureparameters and to hemoglobin concentrations (r = 0.33 and r = 0.38, respectively).Buffered and excess bases in blood were negatively correlated to zinc(r = -0.29 in both cases) and to systolic and diastolic blood pressure (r = -0.31and r = -0.40, respectively). In turn, the systolic and diastolic blood pressurealso correlated negatively to the partial pressure of carbon dioxide and positively to venous blood oxygen saturation and to the partial pressure ofoxygen. The role of zinc and acid-balance realtionships in blood pressure regulationand in arterial hypertension ethiopatogenesis is disscused. [ABSTRACT FROM AUTHOR] |
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