| Autor: |
Homko, Carol J., Panse, Sagar, Santamore, William P., Kashem, Abul, McConnell, Timothy, Bove, Alfred A. |
| Předmět: |
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| Zdroj: |
Diabetes; Jun2007 Supplement 1, Vol. 56, pA656-A656, 1/4p |
| Abstrakt: |
Background: Current evidence suggests that women with diabetes carry a disproportionately increased risk for the development of cardiovascular disease (as compared to both diabetic men and women without diabetes) as well as an increased risk of mortality following an acute cardiac event. The purpose of this study was to examine gender based differences in cardiovascular risk factors and risk factor management among individuals with diabetes but without overt cardiac disease. Methods: The sample consisted of inner city and rural underserved patients with diabetes who were enrolled in a telemedicine trial to reduce CVD risk. All subjects had a 10% or greater CVD risk on the Framingham 10 year absolute risk index but no evidence of overt CVD disease and were required to be under the care of a primary care physician. Assessments included evaluation of height and weight, blood pressure, fasting lipid profile, medication history and Framingham risk assessment. Results: Baseline data were available for 211 individuals with type 2 diabetes (88 males and 123 females). The women and men did not differ in regards to age (61.1 ± 9.6 vs. 59.2 11.0 years), BMI (34.7 ± 7.8 vs. 32.8 ± 5.8 kg/m²), or Framingham risk (20.4 ± 10.9 vs. 21.2 ± 11.5%). Only 37.4% of women and 40.9% of men were at an A1c target of <7%. Total cholesterol levels were significantly higher among females as compared to males (201.4 ± 47.9 vs. 184.7 ± 48.3 mg/dl; p < 0.02) and fewer women were at target (<200 mg/dl) than men (57% versus 73%; p <0.03). In addition, significantly fewer women were treated to an LDL target of<100 mg/dl (32.5 vs. 47.7%, p <0.05) or a BP of < 130/80 mm/Hg (17.9 vs. 28.4%, p < 0.03). Rates of insulin, aspirin, antihypertensive and statin therapy did not differ between the two groups. Conclusion: Fewer women with diabetes are treated to target in regards to LDL and blood pressure than their male counterparts. These data support previous reports that women with diabetes are treated less aggressively than men and this may account for their increased CVD morbidity and mortality. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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