Glucagon-Like Peptide 1 and Exendin-4 Convert Pancreatic AR42J Cells Into Glucagon- and Insulin-Producing Cells.

Autor: Jie ghou, Xiaolin Wang, Pineyro, Marco A., Egan, Josephine M.
Předmět:
Zdroj: Diabetes; Dec99, Vol. 48 Issue 12, p2358, 9p, 3 Color Photographs, 3 Black and White Photographs, 3 Graphs
Abstrakt: Investigates whether glucagon-like peptide 1 (GLP-1) and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells. Effects of GLP-1 and exendin-4 on islet hormone expression; Change in amylase concentration upon incubation of AR42J cells with dexamethasone; Influence of GLP-1 on amylase release from dexamethasone-treated cells.
Databáze: Complementary Index