| Autor: |
Yıldız Dincer, Yusuf Erzin, Solen Himmetoglu, Kezban Gunes, Kadir Bal, Tülay Akcay |
| Předmět: |
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| Zdroj: |
Digestive Diseases & Sciences; Jul2007, Vol. 52 Issue 7, p1636-1641, 6p |
| Abstrakt: |
Abstract Chronic inflammation may contribute to cancer risk through the accumulation of specific products as a result of DNA damage. Endogenous antioxidant enzymes prevent the formation of these harmful products. Oxidative DNA damage and endogenous antioxidant defense were determined in patients with inflammatory bowel disease (IBD). Plasma levels of 8-hydroxydeoxyguanosine (8-OHdG) and nitric oxide (NO) and plasma activities of glutathione peroxidase (G-Px) and superoxide dismutase (SOD) were determined in patients with IBD by ELISA and spectrophotometric assay, respectively. Plasma levels of 8-OHdG, SOD, and G-Px activity were found to be increased in the patient group compared to the control group (P P P [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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