| Autor: |
OGRU, ESRA, LIBINAKI, ROKSAN, GIANELLO, ROBERT, WEST, SIMON, MUNTEANU, ADELINA, ZINGG, JEAN‐MARC, AZZI, ANGELO |
| Předmět: |
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| Zdroj: |
Annals of the New York Academy of Sciences; 2004, Vol. 1031 Issue 1, p405-411, 7p |
| Abstrakt: |
The effect of a mixture of α-tocopheryl phosphate plus di-α-tocopheryl phosphate (TPm) was studied in vitro on two cell lines, RASMC (from rat aortic smooth muscle) and human THP-1 monocytic leukemia cells. Inhibition of cell proliferation by TPm was shown in both lines and occurred with TPm at concentrations lower than those at which α-tocopherol was equally inhibitory. TPm led in nonstimulated THP-1 cells to inhibition of CD36 mRNA and protein expression, to inhibition of oxidized low-density lipoprotein surface binding and oxLDL uptake. In nonstimulated THP-1 cells, α-tocopherol had only very weak effects on these events. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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