| Autor: |
CHARTREL, NICOLAS, BRUZZONE, FEDERICA, DUJARDIN, CYNTHIA, LEPRINCE, JEROME, TOLLEMER, HELENE, ANOUAR, YOUSSEF, VALLARINO, MAURO, COSTENTIN, JEAN, VAUDRY, HUBERT |
| Předmět: |
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| Zdroj: |
Annals of the New York Academy of Sciences; 2005, Vol. 1040 Issue 1, p80-83, 4p |
| Abstrakt: |
In the present study, we report the identification, in the frog brain, of a novel neuropeptide, termed 26RFa, that belongs to the RFamide peptide family. The cDNAs encoding the precursors for 26RFa have been characterized in human and rats. In rats, prepro-26RFa mRNA is expressed exclusively in two hypothalamic nuclei involved in the control of feeding behavior. Intracerebroventricular injection of 26RFa in mice induced a dose-dependent increase in food consumption. Taken together, these data indicate that 26RFa is a novel neuropeptide that may have important biological functions in vertebrates. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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