| Autor: |
GÖKE, RÜDIGER, GREGEL, CORNELIA, GÖKE, ALEXANDRA, ARNOLD, RUDOLF, SCHMIDT, HARALD, LANKAT‐BUTTGEREIT, BRIGITTE |
| Předmět: |
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| Zdroj: |
Annals of the New York Academy of Sciences; 2004, Vol. 1014 Issue 1, p220-221, 2p |
| Abstrakt: |
PDCD4 is a new tumor suppressor gene. In the current study, we show that overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation. This is most likely caused by a PDCD4-induced downregulation of carbonic anhydrase type II which catalyzes the production of bicarbonate, a fundamental substrate for many cellular pathways. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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