Autor: |
Vorona, M., Veinberg, G., Shestakova, I., Kanepe, I., Potorochina, I., Dikovskaya, K., Bokaldere, R., Petrova, M., Liepinsh, E., Lukevics, E. |
Předmět: |
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Zdroj: |
Chemistry of Heterocyclic Compounds; Feb2007, Vol. 43 Issue 2, p207-219, 13p, 1 Chart |
Abstrakt: |
The tert-butyl esters of 3-azidomethyl-, 3-isocyanatomethyl-, 3-chloromethyl-, and 3-p-nitrophenylvinyl-7α-chloro-1,1-dioxoceph-3-em-4-carboxylic acid, and also esters of 7α-chloro-3-methyl-1,1-dioxoceph-3-em-4-carboxylic acid, and of 7α-chloro-3-methyl-2-dimethylaminomethylene-1,1-dioxoceph-3-em-4-carboxylic acid have been synthesized. Results of cytotoxic screening of these compounds in relation to cancer and normal cells in vitro are correlated and analyzed. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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