Perfusion CT to Evaluate the Effect of Transluminal Angioplasty on Cerebral Perfusion in the Treatment of Vasospasm After Subarachnoid Hemorrhage.

Autor: Charles B. L. M. Majoie, Leonard J. van Boven, Diederik van de Beek, Henk W. Venema, Willem J. van Rooij
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Zdroj: Neurocritical Care; Feb2007, Vol. 6 Issue 1, p40-44, 5p
Abstrakt: Introduction: Delayed ischemic neurologic deficits secondary to vasospasm are a majorcause of morbidity and mortality after subarachnoid hemorrhage (SAH). Treatmentof vasospasm after SAH is associated with complications, and reliable techniques forevaluating effects of treatment of vasospasm in such patients are warranted. We presentthe use of perfusion computed tomography (PTC) to evaluate the effect of transluminalpercutaneous angioplasty in a with SAH and vasospasm-induced ischemia.Methods: Dynamic PCT with deconvolution produced maps of time-to-peak, mean transittime, regional cerebral blood flow, and regional cerebral blood volume, with a computerizedautomated map of the infarct and penumbra. CT scanners with quadruple detector arraywere used before and after angioplasty.Results: Before angioplasty and intraarterial papaverine, PCT showed normal to decreasedcerebral blood flow and increased cerebral blood volume and mean transit time in themiddle cerebral artery territory of the left hemisphere. After angioplasty and intraarterialpapaverine, PCT showed normalization of perfusion parameters.Conclusion: PCT can be a useful technique in monitoring angioplasty treatment effectsin patients with vasospasm after SAH. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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