In-VivoRelation between CT Attenuation Value and Shockwave Fragmentation.

Autor: Fernando Hurtado, Jorge Gutiérrez, Eduardo Castaño-Tostado, Julio Bustos, Enrique Mues, María Del Sol Quintero, Arturo Méndez, Achim M. Loske
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Zdroj: Journal of Endourology; Mar2007, Vol. 21 Issue 3, p343-346, 1p
Abstrakt: Purpose To use CT attenuation numbers as a means of determining the susceptibility of an artificial stone to in-vivofragmentation with extracorporeal shockwave lithotripsy (SWL).Materials and Methods Four types of artificial kidney stones having different CT attenuation values were used. One randomly selected stone was implanted in the renal pelvis of a kidney of 12 young pigs and exposed in vivoto 2500 shockwaves (21 kV) using an electrohydraulic lithotripter. Bilateral nephrectomy was performed after SWL. Fragments were strained through a mesh with a 3.1-mm grid, and the debris left on the mesh was dried and weighed. Fragmentation coefficients (FCs) were associated with CT attenuation values using a statistical model.Results The relation between FC and CT number was significant, indicating that as CT attenuation increases, FC is reduced. Larger stone fragments were obtained from stones with higher CT numbers. Initial stone weight was not a significant explanation for variations in FC.Conclusion The CT values could be helpful in selecting patients for SWL in the future. However, other parameters such as stone porosity, shape, and roughness also will have to be considered. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index