| Autor: |
Sathasivam, S., Perkins, D. |
| Předmět: |
|
| Zdroj: |
ANZ Journal of Surgery; May2007 Supplement, Vol. 77, p65-66, 2p |
| Abstrakt: |
Lipomas are benign tumours of the mesenchyme that are composed of mature lipocytes. They are the most common benign mesenchymal tumours with a prevalence rate of 2.1 per 1000 people. The malignant transformation of lipomas to liposarcoma is uncommon. A few reports suggested that large tumours (>10 cm), are more likely to contain sarcomas. Hence, the preoperative biopsy is an essential component of the workup in giant lipomas since it provides key information in determining the treatment protocol. Biopsy can be performed by fine-needle aspiration, core-needle biopsy, incisional biopsy or excisional biopsy. We present four cases where preoperative minimally invasive biopsy techniques were utilised. In these cases, significant differences were noted between preoperative biopsies and the actual histology of the surgically resected specimen. Open biopsies have a relatively higher risk of complication but a smaller chance of misdiagnosis, while needle biopsies are less likely to present with problems but are also frequently less accurate. Given the histological heterogeneity of these tumours, a large sample from a viable area of pathology is recommended for definitive preoperative diagnosis. An open biopsy should be performed through a small incision, designed with consideration of the subsequent definitive operative procedure. A typical incisional biopsy will yield a 1–2 cm3 piece of fresh tissue for the pathologist to reliably exclude the presence of sarcoma in the lesion. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Plný text