Cholinergic syndrome following anticholinergic withdrawal in a schizophrenic patient abusing marijuana.

Autor: Tandon, Rajiv, Dutchak, Denise, Greden, John F., Tandon, R, Dutchak, D, Greden, J F
Předmět:
Zdroj: British Journal of Psychiatry; May89, Vol. 154, p712-714, 3p
Abstrakt: A 27-year-old neuroleptic-stabilised schizophrenic patient presented with a three-day history of psychomotor retardation, disturbed sleep, and social and emotional withdrawal following reduction of his anticholinergic dosage; his symptoms had intensified after an increase in neuroleptic dosage, based on a diagnosis of psychotic decompensation. Recognition of a cholinergic syndrome and institution of appropriate anticholinergic treatment resulted in rapid improvement. The clinical distinction between a cholinergic overdrive state and schizophrenic exacerbation, while sometimes difficult, can be critical in selecting appropriate management. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index