Antidepressant drug therapy in psychotic depression.
| Autor: | Davidson, Jonathan R. T., McLeod, Malcolm M., Kurland, Albert A., White, Helen L., Davidson, J R, McLeod, M N, Kurland, A A, White, H L |
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| Předmět: |
MENTAL depression
ANTIDEPRESSANTS PSYCHIATRIC drugs IMIPRAMINE DEPRESSION in women PLACEBOS AMINE oxidase DRUG therapy for psychoses ORGANIC compounds AFFECTIVE disorders CLINICAL trials COMPARATIVE studies DELUSIONS CLINICAL drug trials RESEARCH methodology MEDICAL cooperation OXIDOREDUCTASES RESEARCH EVALUATION research BLIND experiment DESIPRAMINE THERAPEUTICS |
| Zdroj: | British Journal of Psychiatry; Nov77, Vol. 131, p493-496, 4p |
| Abstrakt: | Imipramine and phenelzine were ineffective in the treatment of five primary unipolar depressives with delusions, even when plasma levels of imipramine and desmethylimipramine or activity of platelet monoamine oxidase suggested that an adequate dose of drug had been given. Four patients went on to receive ECT and all responded well. Five non-delusional patients responded satisfactorily to the antidepressant drug given. Nine out of ten subjects were women. Non-delusional patients showed some placebo response. ECT is considered to be the treatment of choice in the acute phase of delusional depression in women. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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