| Autor: |
Roberto Rivera-Luna, Marta Zapata-Tarrés, Aurora Medina-Sansón, Enrique López-Aguilar, Ana Niembro-Zúñiga, J. Amador Zarco, Alfonso Marhx-Bracho, Fernando Rueda-Franco, Leticia Bornstein-Quevedo |
| Předmět: |
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| Zdroj: |
Child's Nervous System; May2007, Vol. 23 Issue 5, p543-547, 5p |
| Abstrakt: |
Abstract Objective The purpose of this study is to analyze clinical aspects and disease-free survival (DFS) in children less than 3 years of age diagnosed with low-grade astrocytoma. Methods In a period of 24 years (1980–2004), a total of 43 (5.4%) children were registered with these characteristics. Twenty-three patients had pilocytic astrocytoma, 18 diffused, and 2 mixed. Thirty-one (72.1%) children had incomplete surgical tumor resection and 12 (27.9%) had a complete tumor resection. Twelve (27.9%) patients had cranial radiotherapy and 17 (39.5%) received chemotherapy. Overall survival was recorded in 23 (53%). DFS was 50% at 250 months of follow-up for the whole group. DFS for the supratentorial group was 60% at 250 months, whereas, for the infratentorial, it was 22% at 120 months (p = 0.008). Conclusion The only favorable prognostic pattern was the supratentorial presentation. Radiotherapy and chemotherapy did not alter the outcome. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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