The Impact of Varying Dietary Protein on Serum IGF-I, IGFBP-1, and IGFBP-3 During 6 Days of Physical Activity.

Autor: Ormsbee, Michael J., Clapper, Jeffrey A., Clapper, Joan L., Vukovich, Matthew D.
Předmět:
Zdroj: International Journal of Sport Nutrition & Exercise Metabolism; Apr2007, Vol. 17 Issue 2, p127-139, 13p, 2 Charts, 4 Graphs
Abstrakt: This study was designed to investigate the impact of dietary protein intake on serum concentrations of IGF-I and IGFBP-1 and relative amounts of serum IGFBP-3 during 6 d of physical activity. Ten men (23.8 ± 2.0 y of age) were assigned to 1 of 3 trials in a random crossover design. Each trial was isocaloric but with varying amounts of dietary protein: 50 g, 100 g, or 200 g. Subjects expended 500 kcal through treadmill running or weightlifting on alternate days for 6 d. Fasting blood samples were obtained for measurement of IGF-I, IGFBP-1, and IGFBP-3. Pre-post 24-h urine was measured for urea nitrogen. 50 g/d of protein resulted in a negative nitrogen balance, whereas 100 g/d and 200 g/d resulted in a positive nitrogen balance--200 g greater (P < 0.05) than 50 g and 100 g. Baseline IGF-I, BP-1, and BP-3 were not different among treatments. IGF-I decreased (P = 0.002) during the 6 d. Postintervention IGFBP-I was greater (P = 0.03) than at baseline. Postintervention IGFBP-3 values were not different from baseline or between trials. A 6-d modification of protein intake, while in energy balance, during a strength and conditioning program does not appear to modify serum concentrations of IGF-I or IGFBP-1 or relative amounts of IGFBP-3. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index