2D and 3D Refraction Based X-ray Imaging Suitable for Clinical and Pathological Diagnosis.

Autor: Ando, Masami, Bando, Hiroko, Zhihua Chen, Chikaura, Yoshinori, Chang-Hyuk Choi, Endo, Tokiko, Esumi, Hiroyasu, Li Gang, Hashimoto, Eiko, Hirano, Keiichi, Hyodo, Kazuyuki, Ichihara, Shu, SangHoon Jheon, HongTae Kim, JongKi Kim, Kimura, Tatsuro, ChangHyun Lee, Maksimenko, Anton, Ohbayashi, Chiho, SungHwan Park
Předmět:
Zdroj: AIP Conference Proceedings; 2007, Vol. 879 Issue 1, p1899-1902, 4p, 2 Black and White Photographs, 1 Diagram, 1 Chart
Abstrakt: The first observation of micro papillary (MP) breast cancer by x-ray dark-field imaging (XDFI) and the first observation of the 3D x-ray internal structure of another breast cancer, ductal carcinoma in-situ (DCIS), are reported. The specimen size for the sheet-shaped MP was 26 mm × 22 mm × 2.8 mm, and that for the rod-shaped DCIS was 3.6 mm in diameter and 4.7 mm in height. The experiment was performed at the Photon Factory, KEK: High Energy Accelerator Research Organization. We achieved a high-contrast x-ray image by adopting a thickness-controlled transmission-type angular analyzer that allows only refraction components from the object for 2D imaging. This provides a high-contrast image of cancer-cell nests, cancer cells and stroma. For x-ray 3D imaging, a new algorithm due to the refraction for x-ray CT was created. The angular information was acquired by x-ray optics diffraction-enhanced imaging (DEI). The number of data was 900 for each reconstruction. A reconstructed CT image may include ductus lactiferi, micro calcification and the breast gland. This modality has the possibility to open up a new clinical and pathological diagnosis using x-ray, offering more precise inspection and detection of early signs of breast cancer. © 2007 American Institute of Physics [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index