Na,K-ATPase α1-subunit dephosphorylation by protein phosphatase 2A is necessary for its recruitment to the plasma membrane.

Autor: Lecuona, Emilia, Dada, Laura A., Haiying Sun, Butti, Maria L., Guofei Zhou, Teng-Leong Chew, Sznajder, Jacob I.
Předmět:
Zdroj: FASEB Journal; Dec2006, Vol. 20 Issue 14, p2618-2620, 3p, 1 Diagram, 2 Graphs
Abstrakt: The article highlights the findings of a study regarding the significance of sodium,K-adenosine triphosphatease (Na,K-ATPase) α1-subunit dephosphorylation by protein phosphatase 2A (PP2A) to its recruitment to the plasma membrane. It mentions that Na,K-ATPase α1-subunit dephosphorylation is promoted by G-protein coupled-receptor agonists by PP2A at Serine 18 in alveolar epithelial cells.
Databáze: Complementary Index