Evolution of Gonadal Axis After Sex Reassignment Surgery in Transsexual Patients in the Spanish Public Health System.

Autor: Esteva, I., Yahyaoui, R., Cano, G., Giraldo, F., Bergero, R., Ruiz de Adana, S., Rojo, G., Gonzalo, M., Lara, J., Soriguer, F.
Předmět:
Zdroj: International Journal of Transgenderism; 2006, Vol. 9 Issue 2, p15-22, 8p, 4 Charts, 6 Graphs
Abstrakt: Although the effects of hormone therapy on cardiovascular risk factors and bone metabolism have been studied, data are lacking on the gonadotropin profile after gonadectomy in the sex reassignment process (SRP). Accordingly, whether measurement of the gonadotropin pro- file is useful in order to adjust the posesurgical dose of gonadal hormones is unknown. We studied the evolution of LH, FSH, prolactin, testosterone, and estradiol in 50 transsexual persons, 41 male-to-female transsexuals (MtF) and 9 female-to-male transsexuals (FtM), following a protocolized regimen of hormone therapy for 12-24 months before and after genitoplasty. The increase in gonadotropins after surgery was greater in the FEM than in the MtF (66% vs. 50%), with the increase continuing more than one year after surgery. No variable was significantly associated with this different level of gonadotropins. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index