Low dose botulinum toxin in spasmodic torticollis.

Autor: D'Costa, D. F., Abbott, R. J.
Předmět:
Zdroj: Journal of the Royal Society of Medicine; Nov1991, Vol. 84 Issue 11, p650-651, 2p
Abstrakt: Botulinum toxin has been successfully used to treat spasmodic torticollis. The optimum dosage is not clear and the recommended doses in the United Kingdom are 20-25 ng. We have used much lower doses (average 13 ng) without loss of efficacy and accompanied by a reduction in side effects. We treated 12 patients (eight women and four men) with a mean duration of torticollis of 4 years. Eleven of the 12 patients (91%) showed an improvement in total scores for pain and degree of head movement. The benefits appeared a week after treatment and lasted for 3 months. Side effects were minimal and transient. Our experience suggests low doses of the toxin may be equally efficacious. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index