| Autor: |
Doralice Rodrigues Sacramento, Rosalie Reed Rodrigues Coelho, Márcia Dutra Wigg, Luiz Fernando de Toledo Luna Linhares, Marta Gonçalves Matos dos Santos |
| Zdroj: |
World Journal of Microbiology & Biotechnology; Apr2004, Vol. 20 Issue 3, p225-229, 5p |
| Abstrakt: |
A promising producer of bioactive compounds isolated from a Brazilian tropical soil was tested for its range of antimicrobial activities. Strain 606, classified as Streptomyces sp., could not be identified up to species level, suggesting a possible new taxon. The supernatant and 10 extracts and fractions, obtained by extraction and chromatographic techniques, presented antimicrobial activity using antibiograms. The methanolic fraction was highly active against pathogenic bacteria, phytopathogenic fungi and the human pathogenic yeast Candida albicans. It also possessed high antiviral activity inhibiting the propagation of an acyclovir-resistant herpes simplex virus type 1 strain on HEp-2 cells at non-cytotoxic concentration. The strong cytotoxic effect suggests an antitumour action. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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