Magnetic resonance imaging to evaluate NASHA/Dx gel (ZuidexTM) for stress urinary incontinence.

Autor: Fianu-Jonasson, A., Edwall, L., Wiberg, M. Kristoffersen
Předmět:
Zdroj: International Journal of Clinical Practice; Oct2006, Vol. 60 Issue 10, p1181-1186, 6p, 2 Diagrams, 3 Charts
Abstrakt: The ZuidexTM 1 system for the treatment of stress urinary incontinence consists of non-animal stabilised hyaluronic acid/dextranomer (NASHA/Dx) gel and a precision guide, the ImplacerTM 1 . Whether the Implacer accurately deposits NASHA/Dx gel in the desired location within the urethral wall was investigated by magnetic resonance imaging (MRI), performed at a mean of 35 days post-treatment. Three or more deposits were observed in 11 of 16 patients (68.8%), with 39 of the 50 deposits clearly located within the urethral wall, as intended. Fourteen of 16 patients (87.5%) demonstrated improvement in their incontinence at 3 months, sustained at 12 months in 13 patients. No significant correlations between total implant volume and improvements in incontinence were observed at 3 months (p ≥ 0.16) and 12 months (p ≥ 0.30). In conclusion, accurate placement of NASHA/Dx gel into the desired location within the urethral wall was achieved in the majority of cases using the Implacer device, without endoscopic guidance. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index