The genetic association between alpha-2-macroglobulin (A 2 M) gene deletion polymorphism and low serum A 2 M concentration in overweight/obese Thais.

Autor: Rugsarash, Wilaiwan, Tungtrongchitr, Rungsunn, Petmitr, Songsak, Phonrat, Benjaluck, Pongpaew, Praneet, Harnroongroj, Talabporn, Tungtrongchitr, Anchalee
Předmět:
Zdroj: Nutritional Neuroscience; Feb2006, Vol. 9 Issue 1/2, p93-98, 6p, 1 Black and White Photograph, 3 Charts, 1 Graph
Abstrakt: The study subjects were 192 overweight and obese Thais (BMI > 25.00 kg/m 2 ), and 103 Thai controls (BMI = 18.50–24.99 kg/m 2 ), whose ages ranged from 18–60 years. All subjects were evaluated for serum Alpha-2-macroglobulin (A 2 M), globulin, albumin concentration, and polymorphic variation in the A 2 M gene. Serum A 2 M and albumin were significantly lower in the overweight/obese group ( P [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index