Reduced cholesterol accumulation by leptin deficient (ob/ob) mouse macrophages.
Autor: | M. Kjerrulf, Z. Berke, A. Aspegren, M. Umaerus, T. Nilsson, L. Svensson, E. Hurt-Camejo |
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Zdroj: | Inflammation Research; Jul2006, Vol. 55 Issue 7, p300-309, 10p |
Abstrakt: | Abstract. Objective Although presenting many aspects of the metabolic syndrome, leptin deficient (ob/ob) mice do not spontaneously develop atherosclerosis. To examine the role of leptin in foam cell formation we analyzed ob/ob leukocyte inflammation markers and macrophage cholesterol accumulation. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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