Pharmacological Regulation of Functional Activity of Stem Cells in Restoration of the Myocardium during the Postinfarction Period.

Autor: L. Stavrova, T. Fomina, M. Plotnikov, O. Aliev, N. Sotnikova, O. Epstein, S. Sergeeva, L. Gur'yantseva, G. Zyuz'kov, V. Zhdanov, A. Dygai, E. Gol'dberg
Zdroj: Bulletin of Experimental Biology & Medicine; Nov2005, Vol. 140 Issue 5, p593-597, 5p
Abstrakt: The effect of granulocytic CSF on myocardial tissue recovery after acute myocardial infarction was studied on rats. A course of granulocytic CSF after ligation of the left coronary artery normalized ECG parameters and morphological picture of the myocardium 1 month after treatment. It was shown on mouse model of myocardial infarction that this process was associated with more intensive mobilization and homing of mesenchymal stem cells in the heart. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index