| Autor: |
Dwyer, R., Örtqvist, Å., Aufwerber, E., Normark, B. Henriques, Marrie, T. J., Mufson, M. A., Torres, A., Woodhead, M. A., Ålenius, M., Kalin, M. |
| Předmět: |
|
| Zdroj: |
European Journal of Clinical Microbiology & Infectious Diseases; Aug2006, Vol. 25 Issue 8, p518-521, 4p, 2 Charts |
| Abstrakt: |
In the study presented here, data collected prospectively from 340 adult patients hospitalised in five countries with bacteremic pneumococcal CAP and treated with a ß-lactam +/− a macrolide were analysed retrospectively to evaluate the efficacy of this antimicrobial combination. Univariate and multivariate analyses revealed no significant effect on case fatality rate when a macrolide/ß-lactam regimen was used as initial therapy. Results were not affected by severity of illness, or by excluding patients who died within 2 days of admission. Identified predictors of death in a multivariate regression model were age >65 years (OR=2.6), two or more lung lobes affected (OR=2.2), and severity of disease as estimated using the acute physiology score (APS)>8. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink