Fluorescent Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial TherapyWe gratefully acknowledge financial support for this work from the following agencies: the Hans-Fischer Gesellschaft e.V. (to J.K.), The Wellcome Trust (to W.N.H.), the Biotechnology and Biological Sciences Research Council (UK) (to W.N.H.), and InPharmatica (to W.N.H.). The authors also thank Prof. D. Arigoni and Dr. L. Kemp for help and advice. IspF=2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase.

Autor:	Christine M. Crane, Johannes Kaiser, Nicola L. Ramsden, Susan Lauw, Felix Rohdich, Wolfgang Eisenreich, William N. Hunter, Adelbert Bacher, François Diederich
Zdroj:	Angewandte Chemie International Edition; Jan2006, Vol. 45 Issue 7, p1069-1074, 6p
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text