A comparative study of the inducing effect of homoserine lactone and hexylresorcinol on phenotypic dissociation in bacteria.

Autor: Margulis, A. B., Kolpakov, A. I., Il'inskaya, O. N.
Předmět:
Zdroj: Microbiology (00262617); Jul2006, Vol. 75 Issue 4, p401-404, 4p, 1 Black and White Photograph, 1 Chart
Abstrakt: It has been shown that the phenotypic dissociation of Bacillus subtilis SK1 and Salmonella typhimurium TA100 is induced by hexylresorcinol, an exogenous non-species-specific autoregulator of pleiotropic action, which is genotoxic for both pro-and eukaryotes. Nongenotoxic homoserine lactone, a chemical analogue of cell-density-responsive species-specific regulators, does not induce bacterial dissociation. The phage resistance of the S-and R-type variants of S. typhimurium TA100 induced by hexylresorcinol has been found to be the same as that of the S-and R-type salmonella variants obtained by the routine subculturing method. [ABSTRACT FROM AUTHOR]
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