| Autor: |
Tamura, Motoi, Saitoh, Hiroyuki, Tsushida, Tojiro, Shinohara, Kazuki |
| Předmět: |
|
| Zdroj: |
Microbial Ecology in Health & Disease; Apr2006, Vol. 18 Issue 1, p42-46, 5p, 2 Graphs |
| Abstrakt: |
Recently, there has been great interest in the biological effects of equol, a metabolite of daidzein produced by intestinal flora. In this study, we used a newly isolated intestinal bacterium from healthy human faeces to investigate the effects of intestinal bacteria on the in vitro metabolism of daidzein by faecal flora in mice and a human male equol producer. The 16S rDNA partial sequence (1394 bp) of strain TM-20 that was isolated from infant faeces exhibited a 99% similarity to that of Bifidobacterium pseudocatenulatum . Therefore, this strain was identified as belonging to the genus Bifidobacterium . In faecal suspensions from mice, equol concentrations were significantly lower in the control faecal suspension than in the faecal suspension supplemented with the high concentration of strain TM-20. However, equol concentrations were significantly higher in the control faecal suspension than in the faecal suspension supplemented with the low concentration of strain TM-20. In faecal suspensions from a human male equol producer, equol concentrations were lower in the control faecal suspension than in the faecal suspension supplemented with the high concentration of strain TM-20. However, equol concentrations were higher in the control faecal suspension than in the fecal suspension supplemented with the low concentration of strain TM-20. Metabolic activity of the faecal equol production in mice and humans may be changed by some types of bifidobacteria. To our knowledge, this is the first report of a Bifidbacterium sp. that is capable of changing the faecal equol production from daidzein in vitro . [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
