| Autor: |
Jorenby, Douglas E., Hays, J. Taylor, Rigotti, Nancy A., Azoulay, Salomon, Watsky, Eric J., Williams, Kathryn E., Billing, Clare B., Gong, Jason, Reeves, Karen R. |
| Předmět: |
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| Zdroj: |
JAMA: Journal of the American Medical Association; 7/5/2006, Vol. 296 Issue 1, p56-63, 8p, 1 Diagram, 4 Charts, 2 Graphs |
| Abstrakt: |
The article presents a study comparing the safety and effectiveness of varenicline with sustained-release bupropion (bupropion SR) and placebo for smoking cessation. Varenicline is an α2β2 nicotinic acetylcholine receptor partial agonist. Varenicline decreases nicotine withdrawal symptoms and lowers the rewarding properties of nicotine. The study found that varenicline is a safe smoking cessation pharmacotherapy and was more effective than the placebo and bupropion SR for smoking cessation. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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