Isolation and Characterization of Pre-rapamycin, the First Macrocyclic Intermediate in the Biosynthesis of the Immunosuppressant Rapamycin by S. hygroscopicus ( We thank Paul Gates for help with FT-ion cyclotron resonance experiments and Sarah J. Ready for strain preparation. This work was funded in part by project grants from the BBSRC (to P.F.L.). )

Autor: Matthew A. Gregory, Sabine Gaisser, Rachel E. Lill, Hui Hong, Rose M. Sheridan, Barrie Wilkinson, Hrvoje Petkovic, Alison J. Weston, Isabelle Carletti, Huai-Lo Lee, James Staunton, Peter F. Leadlay
Zdroj: Angewandte Chemie; May2003, Vol. 116 Issue 19, p2605-2607, 3p
Databáze: Complementary Index