| Autor: |
Forster, Katrin, Poppert, Holger, Conrad, Bastian, Sander, Dirk |
| Předmět: |
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| Zdroj: |
Journal of Neurology; Jun2006, Vol. 253 Issue 6, p741-745, 5p, 4 Charts, 1 Graph |
| Abstrakt: |
Several studies have reported infection as a possible risk factor for cervical artery dissection (CAD). We retrospectively analyzed several inflammatory parameters of CAD patients with the aim of detecting differences between spontaneous (n = 25) and traumatic (n = 18) CAD. In this case–control study, we observed significantly higher absolute leucocyte values (10.3 versus 8.1 G/L; p = 0.02) as well as an elevated frequency of leucocytosis (64% versus 28%; p = 0.02) and elevated CRP (60% versus 28%; p = 0.04) in patients without a history of trauma ("spontaneous" CAD) compared with patients with traumarelated CAD. As the elevated inflammatory laboratory parameters were not associated with an elevated infection rate, these findings imply a role of an acute inflammation as a pathogenetic factor in spontaneous CAD. The cause and mechanism of the inflammatory process remain unknown. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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